THOC2

Across TCGA patient cohorts, THOC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,608 significant associations in total. GBM shows the largest number of these associations.

The most reproducible THOC2-associated proteins across cancer lineages are THOC7, THOC6, and CSTF2. Each is linked with THOC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both THOC2-to-partner and partner-to-THOC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THOC2 versus THOC7 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THOC2→partner) and Y-score (partner→THOC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	THOC7 →	+0.226	+0.322	<.001	<.001	3	7
LSCC	THOC6 →	+0.226	+0.356	<.001	<.001	3	7
HNSC	CSTF2 →	+0.244	+0.391	<.001	.008	3	7
LSCC	HTATSF1 →	+0.391	+0.450	<.001	<.001	3	7
LSCC	THOC1 →	+0.272	+0.429	<.001	<.001	3	6
OV	FAM50A →	+0.412	+0.481	.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,608 associations by consensus.

THOC2 vs THOC7 — LSCC

Explore this scatter interactively →