Across TCGA cell cohorts, THNSL1 mutation is significantly associated with the drug of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible THNSL1-associated genes across cancer lineages are QL-XII-61, Talazoparib, and MN-64. Each is linked with THNSL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both THNSL1-to-partner and partner-to-THNSL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THNSL1→partner) and Y-score (partner→THNSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	QL-XII-61 →	+0.438	+2.491	.013	.049	3	1
LARGE_INTESTINE	Talazoparib →	+0.745	+2.871	.005	.021	3	1
LARGE_INTESTINE	MN-64 →	+0.345	+2.672	.014	.039	3	1
LARGE_INTESTINE	Teniposide →	+0.710	+2.871	.004	.021	2	1
LARGE_INTESTINE	Docetaxel →	+1.100	+2.807	.020	.045	2	1
LARGE_INTESTINE	615590 →	+0.293	+2.871	.031	.021	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

THNSL1 survival (RNA) · tumor vs normal (RNA) · all THNSL1 data types