Q-omics provides the consensus-scored THEM7P profile across patient tissues and cancer cell-line models. THEM7P expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, THEM7P is differentially expressed in 10, with the highest sampling consensus in KIRC. Additionally, THEM7P RNA expression shows 11,747 significant protein co-abundance associations, with the highest sampling consensus in LUAD. Together, these results highlight MESO, KIRC, and LUAD as cancer lineages where THEM7P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for THEM7P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes THEM7P survival associations across molecular data types. THEM7P RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible THEM7P RNA expression–survival associations across cancer types. High THEM7P expression shows unfavorable associations in MESO, HNSC and KIRP, but favorable associations in UCS, LGG and CHOL. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for THEM7P RNA expression.
This table summarizes THEM7P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for THEM7P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. THEM7P shows higher tumor expression in KIRC, LUAD, LIHC, COAD, HNSC and BRCA. The KIRC box plot shows higher THEM7P RNA expression in tumor versus normal tissue (log2 FC = +0.098, t-test p < 0.001).
This table shows molecular features associated with THEM7P in patient tissues and cancer cell lines. In patient samples, THEM7P shows the broadest associations at the RNA and protein expression levels, with LUAD recurring as the lineage with the largest associated feature set.
