THEM4

Across TCGA patient cohorts, THEM4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,154 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible THEM4-associated proteins across cancer lineages are ANP32E, RO60, and SNX27. Each is linked with THEM4 in more than 5 cancer types. Because this analysis shows association rather than direction, both THEM4-to-partner and partner-to-THEM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THEM4 versus ANP32E in LUAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THEM4→partner) and Y-score (partner→THEM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ANP32E →	+0.652	+0.593	<.001	<.001	3	6
UCEC	RO60 →	+0.260	+0.536	<.001	<.001	3	5
UCEC	SNX27 →	+0.239	+0.678	.002	<.001	3	5
UCEC	RPRD2 →	+0.296	+0.843	<.001	<.001	3	5
UCEC	PRUNE1 →	+0.320	+0.714	.002	<.001	2	5
UCEC	UCHL5 →	+0.312	+0.757	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,154 associations by consensus.

THEM4 vs ANP32E — LUAD

Explore this scatter interactively →