Across TCGA patient cohorts, THBS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,082 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible THBS2-associated proteins across cancer lineages are RCN3, CNN2, and COL16A1. Each is linked with THBS2 in more than 9 cancer types. Because this analysis shows association rather than direction, both THBS2-to-partner and partner-to-THBS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THBS2→partner) and Y-score (partner→THBS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RCN3 →	+0.807	+0.753	<.001	<.001	3	10
OV	CNN2 →	+1.024	+2.602	<.001	<.001	3	10
CCRCC	COL16A1 →	+1.023	+1.597	<.001	<.001	3	10
GBM	COL3A1 →	+1.168	+0.888	<.001	<.001	3	10
BRCA	COL5A1 →	+1.267	+1.993	<.001	<.001	3	10
GBM	COL6A3 →	+0.986	+0.685	.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,082 associations by consensus.

Exploration

THBS2 survival (RNA) · tumor vs normal (RNA) · all THBS2 data types