Across TCGA patient cohorts, THBS2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,843 significant associations in total. COAD shows the largest number of these associations.

The most reproducible THBS2-associated genes across cancer lineages are CCN4, COL1A1, and FN1. Each is linked with THBS2 in more than 9 cancer types. Because this analysis shows association rather than direction, both THBS2-to-partner and partner-to-THBS2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THBS2→partner) and Y-score (partner→THBS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCN4 →	+1.412	+1.556	<.001	<.001	3	10
OV	COL1A1 →	+2.396	+1.430	<.001	<.001	3	10
OV	FN1 →	+2.312	+1.567	<.001	<.001	3	10
OV	INHBA →	+2.304	+1.726	<.001	<.001	3	10
OV	COL10A1 →	+2.708	+1.508	<.001	<.001	3	10
OV	COL5A1 →	+2.049	+1.575	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,843 associations by consensus.

Exploration

THBS2 survival (RNA) · tumor vs normal (RNA) · all THBS2 data types