Across TCGA cell cohorts, THBS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,325 significant associations in total. BONE shows the largest number of these associations.

The most reproducible THBS2-associated GO terms across cancer lineages are Aorta smooth muscle tissue morphogenesis, Regulation of cell-matrix adhesion, and Regulation of cell-substrate junction organization. Each is linked with THBS2 in more than 9 cancer types. Because this analysis shows association rather than direction, both THBS2-to-partner and partner-to-THBS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THBS2→partner) and Y-score (partner→THBS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Aorta smooth muscle tissue morphogenesis →	+0.970	+3.227	<.001	.006	3	10
BONE	Regulation of cell-matrix adhesion →	+0.196	+4.354	<.001	<.001	3	9
BONE	Regulation of cell-substrate junction organization →	+0.191	+4.377	<.001	<.001	3	9
LIVER	Myotube cell development →	+0.118	+2.543	<.001	.004	3	8
BONE	Regulation of intracellular transport →	+0.066	+3.202	.001	.008	3	8
LUNG_NSCLC_LUSC	Regulation of plasminogen activation →	+0.344	+2.286	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,325 associations by consensus.

Exploration

THBS2 survival (RNA) · tumor vs normal (RNA) · all THBS2 data types