THBD

Across TCGA pan-cancer cohorts, THBD Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated THBD data layer compared with 27 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher THBD Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated THBD expression acts as an unfavorable survival marker.

LUAD and STAD are the cancer types where THBD Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.147	0.709	<.001	24	view →
STAD	OS	Median	III,IV	0.075	0.633	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

THBD–LUAD (OS)

Open the LUAD breakdown →