THAP9

Across TCGA patient cohorts, THAP9 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,914 significant associations in total. GBM shows the largest number of these associations.

The most reproducible THAP9-associated proteins across cancer lineages are EPS15_S221, RPRD2, and SRSF7. Each is linked with THAP9 in more than 6 cancer types. Because this analysis shows association rather than direction, both THAP9-to-partner and partner-to-THAP9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THAP9 versus EPS15_S221 in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP9→partner) and Y-score (partner→THAP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EPS15_S221 →	-0.327	-0.381	.001	.001	3	7
LSCC	RPRD2 →	+0.350	+0.711	<.001	<.001	3	6
GBM	SRSF7 →	+0.355	+0.489	<.001	<.001	3	6
GBM	ACTR3 →	-0.183	-0.358	<.001	<.001	3	6
GBM	UNC13D →	-0.397	-0.496	.002	<.001	3	6
GBM	PLIN3 →	-0.477	-0.553	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,914 associations by consensus.

THAP9 vs EPS15_S221 — GBM

Explore this scatter interactively →