THAP9

Across TCGA patient cohorts, THAP9 mutation is significantly associated with the RNA expression of many other genes, with 3,976 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible THAP9-associated genes across cancer lineages are RNA5SP436, LINC02582, and TRAJ12. Each is linked with THAP9 in more than 2 cancer types. Because this analysis shows association rather than direction, both THAP9-to-partner and partner-to-THAP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP436 grouped by THAP9-low versus THAP9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP9→partner) and Y-score (partner→THAP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP436 →	+0.239	+2.414	<.001	.007	3	3
COAD	LINC02582 →	+0.832	+3.777	.007	.005	3	3
CESC	TRAJ12 →	+0.499	+3.608	.001	.004	3	2
CESC	ZNF92P1Y →	+0.025	+6.174	<.001	<.001	3	2
CESC	DNAJA1P1 →	+0.033	+4.306	<.001	.001	3	2
HNSC	CBX3P8 →	+0.061	+5.221	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,976 associations by consensus.

RNA5SP436 by THAP9 expression — UCEC

Explore this box plot interactively →