Across TCGA patient cohorts, THAP7 mutation is significantly associated with the RNA expression of many other genes, with 167 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible THAP7-associated genes across cancer lineages are LAP3P2, EDA, and THBS3. Each is linked with THAP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both THAP7-to-partner and partner-to-THAP7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP7→partner) and Y-score (partner→THAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LAP3P2 →	+0.071	+5.145	<.001	.007	3	2
UCEC	EDA →	-0.916	-2.689	<.001	.006	3	1
UCEC	THBS3 →	-0.796	-3.568	.002	.002	3	1
UCEC	EHBP1L1 →	-0.603	-3.785	.001	<.001	3	1
UCEC	HES3 →	+0.104	+2.109	.001	.008	3	1
UCEC	PHLDB3 →	-0.526	-3.451	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 167 associations by consensus.

Exploration

THAP7 survival (RNA) · tumor vs normal (RNA) · all THAP7 data types