Across TCGA patient cohorts, THAP7 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible THAP7-associated genes across cancer lineages are ACC1, Notch1, and Annexin-1. Each is linked with THAP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both THAP7-to-partner and partner-to-THAP7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP7→partner) and Y-score (partner→THAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.554	+2.459	.001	.020	3	1
UCEC	Notch1 →	+0.165	+3.013	.015	.018	3	1
UCEC	Annexin-1 →	+0.550	+3.019	.030	.019	3	1
UCEC	XBP1 →	-0.183	-2.986	.007	.035	3	1
UCEC	p62 Lck ligand →	+0.429	+2.459	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

THAP7 survival (RNA) · tumor vs normal (RNA) · all THAP7 data types