Across TCGA cell cohorts, THAP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,965 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible THAP7-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Positive regulation of macrophage proliferation. Each is linked with THAP7 in more than 18 cancer types. Because this analysis shows association rather than direction, both THAP7-to-partner and partner-to-THAP7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP7→partner) and Y-score (partner→THAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Symbiont-mediated disruption of host cellular anatomical structure →	+0.191	+1.363	<.001	<.001	3	19
OESOPHAGUS	Symbiont-mediated disruption of host anatomical structure →	+0.191	+1.363	<.001	<.001	3	19
LARGE_INTESTINE	Positive regulation of macrophage proliferation →	+0.201	+1.038	<.001	<.001	3	12
OVARY	Interleukin-34-mediated signaling pathway →	+0.174	+0.943	<.001	.002	3	12
URINARY_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.148	+0.863	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of macrophage proliferation →	+0.180	+0.851	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,965 associations by consensus.

Exploration

THAP7 survival (RNA) · tumor vs normal (RNA) · all THAP7 data types