Across TCGA cell cohorts, THAP7 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible THAP7-associated genes across cancer lineages are S100G and PABPC1L2B. Each is linked with THAP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both THAP7-to-partner and partner-to-THAP7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP7→partner) and Y-score (partner→THAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	S100G →	+0.183	+5.321	<.001	.005	3	2
UPPER_AERODIGESTIVE_TRACT	PABPC1L2B →	+0.099	+4.736	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

THAP7 survival (RNA) · tumor vs normal (RNA) · all THAP7 data types