THAP4

Across TCGA patient cohorts, THAP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,712 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible THAP4-associated proteins across cancer lineages are DTYMK, NCKAP1L, and ORC5. Each is linked with THAP4 in more than 4 cancer types. Because this analysis shows association rather than direction, both THAP4-to-partner and partner-to-THAP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THAP4 versus DTYMK in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP4→partner) and Y-score (partner→THAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DTYMK →	+0.550	+0.693	<.001	<.001	3	5
GBM	NCKAP1L →	-0.534	-0.219	.002	.002	3	4
LSCC	ORC5 →	+0.388	+0.552	<.001	<.001	3	4
LUAD	ADAP2 →	-0.273	-0.286	.007	.002	3	4
CCRCC	CALR →	-0.273	-0.271	.001	.004	3	4
GBM	CAPZA1 →	-0.307	-0.273	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,712 associations by consensus.

THAP4 vs DTYMK — OV

Explore this scatter interactively →