THAP3

Across TCGA patient cohorts, THAP3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,173 significant associations in total. GBM shows the largest number of these associations.

The most reproducible THAP3-associated genes across cancer lineages are RSPH14, TIMM9, and ARHGAP5. Each is linked with THAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both THAP3-to-partner and partner-to-THAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THAP3 versus RSPH14 in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP3→partner) and Y-score (partner→THAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RSPH14 →	+0.600	+0.514	.008	.004	3	1
UCEC	TIMM9 →	-0.306	-0.391	.006	.005	3	1
UCEC	ARHGAP5 →	-0.392	-0.506	.006	.004	3	1
UCEC	USP14 →	-0.595	-0.425	.001	.001	3	1
UCEC	RNMT →	-0.413	-0.541	.001	.003	3	1
UCEC	KLF8 →	-0.747	-0.366	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,173 associations by consensus.

THAP3 vs RSPH14 — UCEC

Explore this scatter interactively →