THAP3

Across TCGA cell cohorts, THAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,162 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible THAP3-associated GO terms across cancer lineages are Regulation of body fluid levels, Response to methionine, and Cellular response to methionine. Each is linked with THAP3 in more than 9 cancer types. Because this analysis shows association rather than direction, both THAP3-to-partner and partner-to-THAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of body fluid levels grouped by THAP3-low versus THAP3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP3→partner) and Y-score (partner→THAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of body fluid levels →	-0.073	-0.439	.001	.004	3	10
STOMACH	Response to methionine →	+0.109	+0.627	.001	.005	2	10
STOMACH	Cellular response to methionine →	+0.109	+0.627	.001	.005	2	10
SOFT_TISSUE	RISC complex assembly →	+0.105	+0.387	<.001	.007	3	9
KIDNEY	Macropinocytosis →	-0.096	-0.600	.008	.001	2	10
LUNG_NSCLC_LUSC	Positive regulation of protein localization to cilium →	+0.139	+0.844	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,162 associations by consensus.

Regulation of body fluid levels by THAP3 expression — LIVER

Explore this box plot interactively →