THAP3

Across TCGA cell cohorts, THAP3 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible THAP3-associated genes across cancer lineages are C6orf118. Each is linked with THAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both THAP3-to-partner and partner-to-THAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by THAP3-low versus THAP3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP3→partner) and Y-score (partner→THAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.175	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

C6orf118 by THAP3 expression — LARGE_INTESTINE

Explore this box plot interactively →