THAP2

Across TCGA cell cohorts, THAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,851 significant associations in total. BONE shows the largest number of these associations.

The most reproducible THAP2-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Positive regulation of mitochondrial ATP synthesis coupled electron transport, and Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway. Each is linked with THAP2 in more than 11 cancer types. Because this analysis shows association rather than direction, both THAP2-to-partner and partner-to-THAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by THAP2-low versus THAP2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP2→partner) and Y-score (partner→THAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.183	+0.708	<.001	<.001	3	12
BLOOD_Lymphoma	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.091	+0.596	<.001	<.001	3	10
BONE	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.161	+0.638	<.001	<.001	3	9
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.080	+0.408	.001	.009	3	9
SKIN	Cap-dependent translational initiation →	+0.088	+0.527	<.001	.002	3	9
BONE	Positive regulation of DNA biosynthetic process →	+0.102	+0.616	<.001	.003	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,851 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by THAP2 expression — BONE

Explore this box plot interactively →