Across TCGA pan-cancer cohorts, THAP12P5 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of THAP12P5’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where THAP12P5 RNA is repressed in tumor relative to normal tissue. In most cancer types THAP12P5 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

LUSC, THCA, and LUAD are the cancer types where THAP12P5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in THAP12P5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.072	<.001	7	view →
THCA	Female	All	−0.085	<.001	6	view →
LUAD	Male	II,III,IV	−0.079	.017	3	view →
KICH	All	All	−0.014	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: THAP12P5 RNA expression & survival · all THAP12P5 data types