THAP12P4

Across TCGA pan-cancer cohorts, THAP12P4 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated THAP12P4 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher THAP12P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated THAP12P4 expression acts as an unfavorable survival marker, although some lineages such as PAAD and OV show a favorable association.

LUAD, SKCM, and PAAD are the cancer types where THAP12P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	0.269	0.674	.004	72	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	36	view →
PAAD	DFS	Tertile	All	1.000	0.233	.019	21	view →
COAD	DFS	Tertile	IV	0.035	0.501	<.001	18	view →
KIRC	DFS	Tertile	All	0.677	0.811	.039	15	view →
THCA	DFS	Tertile	III,IV	0.224	0.772	.013	15	view →
OV	OS	Tertile	IV	0.856	0.573	.028	6	view →
STAD	OS	Tertile	III,IV	0.271	0.513	.043	3	view →
KIRP	DFS	Tertile	All	0.308	0.631	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

THAP12P4–LUAD (OS)

Open the LUAD breakdown →