THAP12P2

Across TCGA pan-cancer cohorts, THAP12P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of THAP12P2’s most consistent transcriptional readouts.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where THAP12P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types THAP12P2 is over-expressed in tumor, although a few such as HNSC and THCA show the opposite, repressed pattern.

PRAD, HNSC, and THCA are the cancer types where THAP12P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in THAP12P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PRAD	All	All	+0.014	.043	2	view →
HNSC	Female	All	−0.010	.015	2	view →
THCA	All	All	−0.007	.030	2	view →
ESCA	Female	All	−0.153	.030	1	view →
LIHC	All	All	+0.005	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

THAP12P2–PRAD

Open the PRAD breakdown →