THAP10

Across TCGA patient cohorts, THAP10 protein abundance is significantly associated with the RNA expression of many other genes, with 5,347 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible THAP10-associated genes across cancer lineages are MIR494, RNU6-1336P, and TMEM114. Each is linked with THAP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both THAP10-to-partner and partner-to-THAP10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THAP10 versus MIR494 in CCRCC, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP10→partner) and Y-score (partner→THAP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MIR494 →	-1.137	-1.581	<.001	.004	3	1
CCRCC	RNU6-1336P →	-1.255	-1.616	.002	.006	3	1
CCRCC	TMEM114 →	-0.092	-2.010	.006	.001	3	1
CCRCC	POLR2LP1 →	-1.132	-1.932	.005	.006	3	1
CCRCC	RPL5P23 →	+0.322	+0.535	<.001	<.001	3	1
CCRCC	MIF →	-0.332	-1.655	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,347 associations by consensus.

THAP10 vs MIR494 — CCRCC

Explore this scatter interactively →