THAP10

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, THAP10 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,971 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible THAP10-associated proteins across cancer lineages are WHAMM_S795, WHAMM_S799, and THY1_T73. Each is linked with THAP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both THAP10-to-partner and partner-to-THAP10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THAP10 versus WHAMM_S795 in GBM, with a Pearson correlation of -0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP10→partner) and Y-score (partner→THAP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMWHAMM_S795 →-0.983-0.844<.001<.00132
GBMWHAMM_S799 →-0.983-0.844<.001<.00132
GBMTHY1_T73 →+0.847+0.805<.001<.00131
GBMTIAM1_S695 →-1.135-0.745<.001<.00131
GBMTIAM2_S218 →+0.996+0.544<.001<.00131
GBMTP53BP1_T1214 →+0.696+0.860<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,971 associations by consensus.

THAP10 vs WHAMM_S795 — GBM

Per-sample scatter of THAP10 vs WHAMM_S795 in GBM (Pearson r = -0.73).

Explore this scatter interactively →

Exploration