THADA

Across TCGA patient cohorts, THADA protein abundance is significantly associated with the protein abundance of many other proteins, with 31,438 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible THADA-associated proteins across cancer lineages are BIRC6, TTC27, and XPOT. Each is linked with THADA in more than 7 cancer types. Because this analysis shows association rather than direction, both THADA-to-partner and partner-to-THADA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THADA versus BIRC6 in BRCA, with a Pearson correlation of 0.37.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THADA→partner) and Y-score (partner→THADA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BIRC6 →	+0.207	+0.208	<.001	<.001	3	8
LSCC	TTC27 →	+0.375	+0.237	<.001	<.001	3	7
LSCC	XPOT →	+0.324	+0.211	<.001	<.001	3	7
HNSC	CAD →	+0.401	+0.298	<.001	<.001	3	7
LSCC	NOL11 →	+0.285	+0.235	<.001	<.001	3	7
LSCC	DHX57 →	+0.246	+0.265	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 31,438 associations by consensus.

THADA vs BIRC6 — BRCA

Explore this scatter interactively →