THADA

Across TCGA cell cohorts, THADA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,283 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible THADA-associated GO terms across cancer lineages are tRNA nucleoside ribose methylation, Transcription by RNA polymerase I, and Positive regulation of transcription by RNA polymerase I. Each is linked with THADA in more than 16 cancer types. Because this analysis shows association rather than direction, both THADA-to-partner and partner-to-THADA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA nucleoside ribose methylation grouped by THADA-low versus THADA-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THADA→partner) and Y-score (partner→THADA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	tRNA nucleoside ribose methylation →	+0.130	+0.887	<.001	<.001	3	17
LARGE_INTESTINE	Transcription by RNA polymerase I →	+0.101	+0.611	<.001	<.001	3	14
BONE	Positive regulation of transcription by RNA polymerase I →	+0.125	+0.603	.004	.001	3	13
BONE	Nucleic acid transport →	+0.122	+0.683	<.001	<.001	3	13
BONE	RNA transport →	+0.122	+0.683	<.001	<.001	3	13
STOMACH	Nuclear export →	+0.096	+0.812	.003	.005	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,283 associations by consensus.

tRNA nucleoside ribose methylation by THADA expression — BONE

Explore this box plot interactively →