THA1P

Across TCGA pan-cancer cohorts, THA1P RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of THA1P’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where THA1P RNA is repressed in tumor relative to normal tissue. In most cancer types THA1P is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, KICH, and THCA are the cancer types where THA1P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in THA1P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.330	<.001	11	view →
KICH	Male	All	−0.530	<.001	10	view →
THCA	All	III,IV	−0.448	<.001	7	view →
LUSC	All	All	−0.335	<.001	7	view →
HNSC	All	All	+0.117	.002	7	view →
BRCA	All	III,IV	−0.323	<.001	6	view →
KIRP	Male	All	−0.289	.014	4	view →
KIRC	Male	II,III,IV	−0.180	.005	4	view →
CHOL	Female	All	+0.450	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

THA1P–LUAD

Open the LUAD breakdown →