TGS1

Across TCGA patient cohorts, TGS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,333 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGS1-associated proteins across cancer lineages are YTHDF3, GATAD2B, and PUS7. Each is linked with TGS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TGS1-to-partner and partner-to-TGS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGS1 versus YTHDF3 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGS1→partner) and Y-score (partner→TGS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YTHDF3 →	+0.245	+0.419	.003	.002	2	8
GBM	GATAD2B →	+0.350	+0.246	<.001	<.001	3	6
LSCC	PUS7 →	+0.409	+0.520	<.001	<.001	3	6
BRCA	VCPIP1 →	+0.349	+0.493	<.001	<.001	3	6
GBM	MSH2 →	+0.613	+0.257	<.001	.001	3	6
LSCC	ATAD2 →	+0.476	+0.447	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,333 associations by consensus.

TGS1 vs YTHDF3 — OV

Explore this scatter interactively →