TGOLN2

Across TCGA patient cohorts, TGOLN2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,522 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TGOLN2-associated genes across cancer lineages are NGDN, COPS6, and REC8. Each is linked with TGOLN2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TGOLN2-to-partner and partner-to-TGOLN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGOLN2 versus NGDN in HNSC, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGOLN2→partner) and Y-score (partner→TGOLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NGDN →	-0.563	-0.212	.005	.003	3	5
UCEC	COPS6 →	-0.643	-0.603	<.001	<.001	3	4
HNSC	REC8 →	-0.571	-0.195	.006	.009	3	3
LUAD	TNNT1 →	-2.205	-0.344	<.001	<.001	3	3
UCEC	TUBA1B →	-1.088	-0.480	.001	.001	3	3
PDAC	FAM110A →	-0.489	-0.348	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,522 associations by consensus.

TGOLN2 vs NGDN — HNSC

Explore this scatter interactively →