TGOLN2

Across TCGA patient cohorts, TGOLN2 mutation is significantly associated with the RNA expression of many other genes, with 2,836 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TGOLN2-associated genes across cancer lineages are RNA5SP402, MIR548AK, and ZNRF2P3. Each is linked with TGOLN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TGOLN2-to-partner and partner-to-TGOLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP402 grouped by TGOLN2-low versus TGOLN2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGOLN2→partner) and Y-score (partner→TGOLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP402 →	+0.388	+5.201	<.001	.007	3	2
SKCM	MIR548AK →	+0.445	+4.614	<.001	.006	3	2
COAD	ZNRF2P3 →	+0.164	+4.418	<.001	.008	3	2
BLCA	MIR4516 →	+0.515	+3.844	<.001	.002	3	2
HNSC	MIR513C →	+0.517	+7.954	<.001	.008	3	1
CESC	TRIM67-AS1 →	+0.037	+5.539	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,836 associations by consensus.

RNA5SP402 by TGOLN2 expression — CESC

Explore this box plot interactively →