TGOLN2

Across TCGA cell cohorts, TGOLN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,443 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TGOLN2-associated GO terms across cancer lineages are Cytosolic transport, Retrograde transport, endosome to Golgi, and Vesicle-mediated transport to the plasma membrane. Each is linked with TGOLN2 in more than 17 cancer types. Because this analysis shows association rather than direction, both TGOLN2-to-partner and partner-to-TGOLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by TGOLN2-low versus TGOLN2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGOLN2→partner) and Y-score (partner→TGOLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytosolic transport →	+0.078	+1.264	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.070	+1.257	<.001	<.001	3	17
BONE	Vesicle-mediated transport to the plasma membrane →	+0.098	+1.849	<.001	<.001	3	16
BONE	Endocytic recycling →	+0.079	+1.673	<.001	<.001	3	16
BLOOD_Myeloma	Vacuolar transport →	+0.058	+0.996	<.001	<.001	3	16
BONE	Protein localization to vacuole →	+0.090	+1.603	.001	.003	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,443 associations by consensus.

Cytosolic transport by TGOLN2 expression — BONE

Explore this box plot interactively →