TGM5

Across TCGA cell cohorts, TGM5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,571 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TGM5-associated GO terms across cancer lineages are Plasma membrane organization, Negative regulation of p38MAPK cascade, and Regulation of response to cytokine stimulus. Each is linked with TGM5 in more than 7 cancer types. Because this analysis shows association rather than direction, both TGM5-to-partner and partner-to-TGM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasma membrane organization grouped by TGM5-low versus TGM5-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM5→partner) and Y-score (partner→TGM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Plasma membrane organization →	+0.078	+0.120	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of p38MAPK cascade →	+0.177	+1.299	<.001	<.001	3	7
SOFT_TISSUE	Regulation of response to cytokine stimulus →	+0.044	+0.100	<.001	.008	3	7
OVARY	Regulation of T cell proliferation →	+0.095	+0.214	.003	.008	3	7
SOFT_TISSUE	Negative regulation of collagen metabolic process →	+0.148	+0.113	<.001	.002	3	6
BLOOD_Lymphoma	Regulation of extracellular matrix disassembly →	+0.112	+0.710	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,571 associations by consensus.

Plasma membrane organization by TGM5 expression — SOFT_TISSUE

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