TGM3

Across TCGA cell cohorts, TGM3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,061 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TGM3-associated genes across cancer lineages are SCP2, GLO1, and SECISBP2. Each is linked with TGM3 in more than 4 cancer types. Because this analysis shows association rather than direction, both TGM3-to-partner and partner-to-TGM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGM3 versus SCP2 in LARGE_INTESTINE, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM3→partner) and Y-score (partner→TGM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SCP2 →	-0.746	-1.225	.004	<.001	3	5
PANCREAS	GLO1 →	-1.821	-1.301	<.001	<.001	3	4
LUNG_SCLC	SECISBP2 →	+0.750	+1.656	.007	.006	3	4
LUNG_SCLC	KLHDC1 →	+0.738	+1.334	.001	.007	3	4
CNS	ATP6V1B1 →	+1.112	+2.166	.001	<.001	3	4
CNS	HAX1 →	+0.479	+1.967	.006	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,061 associations by consensus.

TGM3 vs SCP2 — LARGE_INTESTINE

Explore this scatter interactively →