Across TCGA patient cohorts, TGM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,113 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGM2-associated proteins across cancer lineages are TGM2_S216, WIPF1, and SOD2. Each is linked with TGM2 in more than 9 cancer types. Because this analysis shows association rather than direction, both TGM2-to-partner and partner-to-TGM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM2→partner) and Y-score (partner→TGM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TGM2_S216 →	+1.014	+1.381	<.001	<.001	3	10
BRCA	WIPF1 →	+0.424	+0.840	<.001	<.001	3	8
BRCA	SOD2 →	+0.707	+0.930	<.001	<.001	3	7
GBM	DPYD →	+0.786	+0.956	<.001	<.001	3	7
GBM	GIMAP1 →	+0.613	+1.103	<.001	<.001	3	7
LSCC	GIMAP4 →	+0.613	+1.087	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,113 associations by consensus.

Exploration

TGM2 survival (RNA) · tumor vs normal (RNA) · all TGM2 data types