Across TCGA patient cohorts, TGM2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,072 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGM2-associated genes across cancer lineages are GZMK, ITK, and ARHGAP9. Each is linked with TGM2 in more than 7 cancer types. Because this analysis shows association rather than direction, both TGM2-to-partner and partner-to-TGM2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM2→partner) and Y-score (partner→TGM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GZMK →	+1.125	+0.430	<.001	<.001	3	8
LSCC	ITK →	+0.949	+0.653	<.001	<.001	3	8
OV	ARHGAP9 →	+0.939	+0.682	<.001	<.001	3	8
HNSC	GIMAP6 →	+1.028	+0.705	<.001	<.001	3	8
HNSC	CD3G →	+0.972	+0.638	<.001	<.001	3	8
HNSC	PYHIN1 →	+0.923	+0.758	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,072 associations by consensus.

Exploration

TGM2 survival (RNA) · tumor vs normal (RNA) · all TGM2 data types