TGM1

Across TCGA patient cohorts, TGM1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,695 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TGM1-associated genes across cancer lineages are HECTD2, PTK6, and BMF. Each is linked with TGM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TGM1-to-partner and partner-to-TGM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGM1 versus HECTD2 in HNSC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM1→partner) and Y-score (partner→TGM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HECTD2 →	-0.663	-1.189	<.001	<.001	3	3
OV	PTK6 →	+1.137	+0.852	<.001	.005	3	3
HNSC	BMF →	-0.896	-1.144	<.001	<.001	3	3
OV	FSD1L →	-0.689	-0.960	<.001	.001	3	3
OV	PACSIN1 →	-0.830	-0.951	.002	.002	3	3
HNSC	ELOVL5 →	-0.841	-1.121	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,695 associations by consensus.

TGM1 vs HECTD2 — HNSC

Explore this scatter interactively →