TGM1

Across TCGA cell cohorts, TGM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,177 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TGM1-associated GO terms across cancer lineages are Regulation of nucleocytoplasmic transport, Negative regulation of RNA catabolic process, and Post-transcriptional gene silencing. Each is linked with TGM1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TGM1-to-partner and partner-to-TGM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleocytoplasmic transport grouped by TGM1-low versus TGM1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM1→partner) and Y-score (partner→TGM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of nucleocytoplasmic transport →	+0.072	+0.916	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of RNA catabolic process →	+0.054	+1.926	<.001	<.001	3	12
OESOPHAGUS	Post-transcriptional gene silencing →	+0.090	+1.766	.001	.001	3	12
LARGE_INTESTINE	mRNA transport →	+0.088	+1.051	<.001	<.001	3	12
LIVER	Negative regulation of mRNA metabolic process →	+0.093	+1.174	.005	<.001	2	12
OESOPHAGUS	mRNA splice site recognition →	+0.178	+2.820	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,177 associations by consensus.

Regulation of nucleocytoplasmic transport by TGM1 expression — PANCREAS

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