TGIF2LX

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TGIF2LX protein abundance is significantly associated with the RNA expression of many other genes, with 3,891 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TGIF2LX-associated genes across cancer lineages are SIGLEC5, MAP3K8, and BST1. Each is linked with TGIF2LX in more than 2 cancer types. Because this analysis shows association rather than direction, both TGIF2LX-to-partner and partner-to-TGIF2LX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGIF2LX versus SIGLEC5 in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGIF2LX→partner) and Y-score (partner→TGIF2LX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCSIGLEC5 →+0.152+0.853<.001<.00132
GBMMAP3K8 →+0.993+0.725.005.00432
GBMBST1 →+0.768+0.837<.001<.00132
BRCACD69 →+1.027+0.904<.001<.00132
LSCCRIPOR2 →+0.989+0.734<.001<.00132
BRCAVNN2 →+0.903+0.803<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,891 associations by consensus.

TGIF2LX vs SIGLEC5 — LSCC

Per-sample scatter of TGIF2LX vs SIGLEC5 in LSCC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration