TGIF2LX

Across TCGA patient cohorts, TGIF2LX protein abundance is significantly associated with the protein abundance of many other proteins, with 3,534 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TGIF2LX-associated proteins across cancer lineages are IGHG4, IGHV3-49, and IGHV3-7. Each is linked with TGIF2LX in more than 4 cancer types. Because this analysis shows association rather than direction, both TGIF2LX-to-partner and partner-to-TGIF2LX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGIF2LX versus IGHG4 in LSCC, with a Pearson correlation of 0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGIF2LX→partner) and Y-score (partner→TGIF2LX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IGHG4 →	+1.102	+0.772	<.001	<.001	3	5
UCEC	IGHV3-49 →	+0.991	+1.538	.004	<.001	3	5
GBM	IGHV3-7 →	+1.141	+0.779	<.001	<.001	3	5
LUAD	IGLV1-51 →	+0.879	+1.411	<.001	<.001	3	5
UCEC	C1RL →	+0.500	+1.315	<.001	<.001	3	4
GBM	IGHG1 →	+0.915	+0.818	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,534 associations by consensus.

TGIF2LX vs IGHG4 — LSCC

Explore this scatter interactively →