TGIF2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TGIF2 protein abundance is significantly associated with the RNA expression of many other genes, with 486 significant associations in total. OV shows the largest number of these associations.

The most reproducible TGIF2-associated genes across cancer lineages are CYB5R3, MIOX, and CSTF1. Each is linked with TGIF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TGIF2-to-partner and partner-to-TGIF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGIF2 versus CYB5R3 in OV, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGIF2→partner) and Y-score (partner→TGIF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCYB5R3 →-0.907-0.962.002.00631
OVMIOX →-0.270-0.791.007.00331
OVCSTF1 →+0.640+0.945.001<.00131
OVC20orf27 →+1.158+1.486<.001<.00131
OVMANBAL →+0.879+1.255.002.00131
OVAHCY →+0.632+0.969.004.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 486 associations by consensus.

TGIF2 vs CYB5R3 — OV

Per-sample scatter of TGIF2 vs CYB5R3 in OV (Pearson r = -0.45).

Explore this scatter interactively →

Exploration