TGIF2

Across TCGA cell cohorts, TGIF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,683 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TGIF2-associated GO terms across cancer lineages are DNA-templated transcription initiation, Heterochromatin organization, and Regulation of RNA stability. Each is linked with TGIF2 in more than 12 cancer types. Because this analysis shows association rather than direction, both TGIF2-to-partner and partner-to-TGIF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by TGIF2-low versus TGIF2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGIF2→partner) and Y-score (partner→TGIF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DNA-templated transcription initiation →	+0.070	+1.430	<.001	<.001	3	13
OVARY	Heterochromatin organization →	+0.080	+1.376	<.001	<.001	3	12
BREAST	Regulation of RNA stability →	+0.050	+1.219	<.001	<.001	3	12
OVARY	rRNA transcription →	+0.096	+1.380	<.001	<.001	3	11
BONE	DNA-templated transcription termination →	+0.119	+1.815	<.001	<.001	3	11
BONE	Transcription initiation at RNA polymerase I promoter →	+0.116	+1.549	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,683 associations by consensus.

DNA-templated transcription initiation by TGIF2 expression — OVARY

Explore this box plot interactively →