TGIF1

Across TCGA patient cohorts, TGIF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,791 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGIF1-associated proteins across cancer lineages are RNMT, SMCHD1, and GNAO1. Each is linked with TGIF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TGIF1-to-partner and partner-to-TGIF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGIF1 versus RNMT in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGIF1→partner) and Y-score (partner→TGIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNMT →	+0.309	+0.491	<.001	<.001	3	7
GBM	SMCHD1 →	+0.474	+0.680	<.001	<.001	3	6
GBM	GNAO1 →	-0.547	-0.438	.003	.007	3	5
UCEC	ITGA2 →	+0.648	+0.518	.001	.001	3	5
GBM	OPTN →	-0.389	-0.394	.008	.005	3	5
LUAD	CDYL_S216 →	+0.762	+0.571	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,791 associations by consensus.

TGIF1 vs RNMT — LSCC

Explore this scatter interactively →