TGIF1

Across TCGA patient cohorts, TGIF1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,460 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGIF1-associated genes across cancer lineages are ANKRD9, RPL3, and MRTO4. Each is linked with TGIF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TGIF1-to-partner and partner-to-TGIF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGIF1 versus ANKRD9 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGIF1→partner) and Y-score (partner→TGIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANKRD9 →	+0.754	+0.374	.006	.007	3	3
LUAD	RPL3 →	+0.558	+0.592	.001	.001	3	3
LSCC	MRTO4 →	+0.476	+0.231	.001	.003	3	3
LUAD	RPS20 →	+0.529	+0.470	<.001	.004	3	3
UCEC	EPB41L5 →	+0.506	+0.407	.002	.002	3	2
LSCC	C2orf42 →	+0.400	+0.350	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,460 associations by consensus.

TGIF1 vs ANKRD9 — BRCA

Explore this scatter interactively →