TGFBRAP1

Across TCGA cell cohorts, TGFBRAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,454 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TGFBRAP1-associated GO terms across cancer lineages are Metaphase/anaphase transition of cell cycle, Positive regulation of cytokinesis, and Endosomal vesicle fusion. Each is linked with TGFBRAP1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TGFBRAP1-to-partner and partner-to-TGFBRAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase/anaphase transition of cell cycle grouped by TGFBRAP1-low versus TGFBRAP1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFBRAP1→partner) and Y-score (partner→TGFBRAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Metaphase/anaphase transition of cell cycle →	+0.156	+0.759	<.001	<.001	3	14
BONE	Positive regulation of cytokinesis →	+0.108	+0.596	.005	.001	3	14
OVARY	Endosomal vesicle fusion →	+0.103	+0.837	<.001	<.001	3	13
OESOPHAGUS	Metaphase/anaphase transition of mitotic cell cycle →	+0.167	+1.027	.009	.001	2	14
BONE	Positive regulation of mitotic cytokinesis →	+0.181	+0.708	.003	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Nuclear export →	+0.084	+0.952	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,454 associations by consensus.

Metaphase/anaphase transition of cell cycle by TGFBRAP1 expression — BLOOD_Myeloma

Explore this box plot interactively →