TGFBR3

Across TCGA patient cohorts, TGFBR3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,884 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TGFBR3-associated genes across cancer lineages are RN7SL653P, LRIG1, and APBB2. Each is linked with TGFBR3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TGFBR3-to-partner and partner-to-TGFBR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGFBR3 versus RN7SL653P in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFBR3→partner) and Y-score (partner→TGFBR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL653P →	+1.315	+0.870	<.001	<.001	3	7
BRCA	LRIG1 →	+0.756	+0.520	<.001	<.001	3	4
BRCA	APBB2 →	+0.749	+0.589	.003	<.001	3	4
UCEC	TNXB →	+1.162	+0.733	.005	.002	3	4
CCRCC	PEAR1 →	+0.815	+0.366	.001	<.001	3	4
CCRCC	FRY →	+0.671	+0.355	.007	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,884 associations by consensus.

TGFBR3 vs RN7SL653P — UCEC

Explore this scatter interactively →