TGFBR3

Across TCGA cell cohorts, TGFBR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,662 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TGFBR3-associated GO terms across cancer lineages are Vasculogenesis involved in coronary vascular morphogenesis, Phospholipid biosynthetic process, and ERBB3 signaling pathway. Each is linked with TGFBR3 in more than 10 cancer types. Because this analysis shows association rather than direction, both TGFBR3-to-partner and partner-to-TGFBR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vasculogenesis involved in coronary vascular morphogenesis grouped by TGFBR3-low versus TGFBR3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFBR3→partner) and Y-score (partner→TGFBR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Vasculogenesis involved in coronary vascular morphogenesis →	+1.114	+1.617	<.001	<.001	3	11
STOMACH	Phospholipid biosynthetic process →	+0.049	+1.984	.002	<.001	3	7
URINARY_TRACT	ERBB3 signaling pathway →	+0.177	+1.959	.001	<.001	3	7
URINARY_TRACT	ERBB2-ERBB3 signaling pathway →	+0.177	+1.959	.001	<.001	3	7
LARGE_INTESTINE	Cytosolic transport →	+0.070	+1.741	<.001	<.001	3	6
LIVER	Response to luteinizing hormone →	-0.212	-1.420	.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,662 associations by consensus.

Vasculogenesis involved in coronary vascular morphogenesis by TGFBR3 expression — PANCREAS

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