TGFBR2

Across TCGA patient cohorts, TGFBR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 27,771 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGFBR2-associated proteins across cancer lineages are TLN1, CAVIN1, and CAVIN3. Each is linked with TGFBR2 in more than 9 cancer types. Because this analysis shows association rather than direction, both TGFBR2-to-partner and partner-to-TGFBR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGFBR2 versus TLN1 in GBM, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFBR2→partner) and Y-score (partner→TGFBR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TLN1 →	+0.368	+0.683	<.001	<.001	3	10
BRCA	CAVIN1 →	+0.696	+1.106	<.001	<.001	3	10
BRCA	CAVIN3 →	+0.705	+1.154	<.001	<.001	3	10
UCEC	KANK2 →	+0.556	+0.494	.003	.004	3	10
COAD	RSU1 →	+0.410	+0.597	<.001	<.001	3	9
CCRCC	VCL →	+0.396	+0.469	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,771 associations by consensus.

TGFBR2 vs TLN1 — GBM

Explore this scatter interactively →