TGFBR2

Across TCGA cell cohorts, TGFBR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,753 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TGFBR2-associated GO terms across cancer lineages are Positive regulation of T cell tolerance induction, Regulation of NK T cell differentiation, and Positive regulation of tolerance induction. Each is linked with TGFBR2 in more than 19 cancer types. Because this analysis shows association rather than direction, both TGFBR2-to-partner and partner-to-TGFBR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of T cell tolerance induction grouped by TGFBR2-low versus TGFBR2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFBR2→partner) and Y-score (partner→TGFBR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of T cell tolerance induction →	+2.043	+2.872	<.001	<.001	3	20
BONE	Regulation of NK T cell differentiation →	+1.739	+3.138	<.001	<.001	3	19
BONE	Positive regulation of tolerance induction →	+1.956	+2.958	<.001	<.001	3	19
LUNG_SCLC	Endocardial cushion fusion →	+1.283	+2.326	<.001	.001	3	18
BLOOD_Myeloma	Cell adhesion involved in heart morphogenesis →	+1.218	+2.147	.006	<.001	3	17
BONE	Cartilage development →	+0.138	+3.483	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,753 associations by consensus.

Positive regulation of T cell tolerance induction by TGFBR2 expression — BONE

Explore this box plot interactively →