TGFB3

Across TCGA patient cohorts, TGFB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,290 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TGFB3-associated proteins across cancer lineages are CCDC80, PDLIM7, and KANK2. Each is linked with TGFB3 in more than 9 cancer types. Because this analysis shows association rather than direction, both TGFB3-to-partner and partner-to-TGFB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGFB3 versus CCDC80 in OV, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFB3→partner) and Y-score (partner→TGFB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCDC80 →	+1.040	+1.523	<.001	<.001	3	10
COAD	PDLIM7 →	+0.846	+1.358	<.001	<.001	3	10
BRCA	KANK2 →	+0.637	+1.483	<.001	<.001	3	10
OV	MMP2 →	+1.026	+1.530	<.001	<.001	3	10
UCEC	TPM2 →	+1.229	+0.699	<.001	.001	3	10
GBM	ZYX →	+0.420	+0.618	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,290 associations by consensus.

TGFB3 vs CCDC80 — OV

Explore this scatter interactively →