TGFB3

Across TCGA patient cohorts, TGFB3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,173 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TGFB3-associated genes across cancer lineages are COL5A1, MYL9, and CRISPLD2. Each is linked with TGFB3 in more than 8 cancer types. Because this analysis shows association rather than direction, both TGFB3-to-partner and partner-to-TGFB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGFB3 versus COL5A1 in OV, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFB3→partner) and Y-score (partner→TGFB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COL5A1 →	+2.097	+0.899	<.001	<.001	3	9
UCEC	MYL9 →	+1.420	+0.597	<.001	<.001	3	8
OV	CRISPLD2 →	+1.839	+0.808	<.001	<.001	3	8
OV	CCN4 →	+1.590	+0.942	<.001	<.001	3	8
UCEC	SFRP4 →	+2.876	+0.579	<.001	<.001	3	8
OV	ASPN →	+2.025	+0.676	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,173 associations by consensus.

TGFB3 vs COL5A1 — OV

Explore this scatter interactively →